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    A collaborative study of the EDNAP group regarding Y-chromosome binary polymorphism analysis


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    Reference Type: Journal Article

    Record Number: 17

    Author: M. Brion, B. M. Dupuy, M. Heinrich, C. Hohoff, B. Hoste, B. Ludes, B. Mevag, N. Morling, H. Niederstatter, W. Parson, J. Sanchez, K. Bender, N. Siebert, C. Thacker, C. Vide and A. Carracedo

    Year: 2005

    Title: A collaborative study of the EDNAP group regarding Y-chromosome binary polymorphism analysis

    Journal: Forensic Sci Int

    Volume: 153

    Issue: 2-3

    Pages: 103-8

    Epub Date: 2005/07/19

    Date: Oct 29

    Short Title: A collaborative study of the EDNAP group regarding Y-chromosome binary polymorphism analysis

    ISSN: 0379-0738 (Print)

    DOI: S0379-0738(05)00337-3 [pii], 10.1016/j.forsciint.2005.06.002,

    Accession Number: 16024201

    Keywords: *Chromosomes, Human, Y, *DNA Fingerprinting, Europe, Genetic Markers, *Genetics, Population, Haplotypes, Humans, Male, Polymerase Chain Reaction, *Polymorphism, Single Nucleotide, Reproducibility of Results,

    Abstract: A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories, to be analysed for 11 Y-chromosome single nucleotide polymorphisms (SNPs): SRY-1532, M40, M35, M213, M9, 92R7, M17, P25, M18, M153 and M167. All the labs were also asked to submit a population study including these markers. All participating laboratories reported the same results, indicating the reproducibility and robustness of Y-chromosome SNP typing. A total of 535 samples from six different European populations were also analysed. In Galicia (NW Spain) and Belgium, the most frequent haplogroup was R1b*(xR1b1,R1b3df). Haplogroup F*(xK) is one of the most frequent in Austria and Denmark, while the lowest frequency appear in Belgium. Haplogroup frequencies found in this collaborative study were compared with previously published European Y-chromosome haplogroup data.

    Notes: Brion, Maria, Dupuy, Berit M, Heinrich, Marielle, Hohoff, Carsten, Hoste, Bernardette, Ludes, Bertrand, Mevag, Bente, Morling, Niels, Niederstatter, Harald, Parson, Walther, Sanchez, Juan, Bender, Klaus, Siebert, Nathalie, Thacker, Catherine, Vide, Conceicao, Carracedo, Angel, Multicenter Study, Research Support, Non-U.S. Gov't, Ireland, Forensic science international, Forensic Sci Int. 2005 Oct 29;153(2-3):103-8.,

    Author Address: Institute of Legal Medicine, University of Santiago de Compostela, San Francisco s/n, 15782 Santiago de Compostela, Spain. brioniml@usc.es

    Language: eng