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    Population structure in the Mediterranean basin: a Y chromosome perspective

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    Reference Type: Journal Article

    Record Number: 18

    Author: C. Capelli, N. Redhead, V. Romano, F. Cali, G. Lefranc, V. Delague, A. Megarbane, A. E. Felice, V. L. Pascali, P. I. Neophytou, Z. Poulli, A. Novelletto, P. Malaspina, L. Terrenato, A. Berebbi, M. Fellous, M. G. Thomas and D. B. Goldstein

    Year: 2006

    Title: Population structure in the Mediterranean basin: a Y chromosome perspective

    Journal: Ann Hum Genet

    Volume: 70

    Issue: Pt 2

    Pages: 207-25

    Epub Date: 2006/04/22

    Date: Mar

    Short Title: Population structure in the Mediterranean basin: a Y chromosome perspective

    ISSN: 0003-4800 (Print)

    DOI: AHG224 [pii], 10.1111/j.1529-8817.2005.00224.x,

    Accession Number: 16626331

    Keywords: *Chromosomes, Human, Y, Ethnic Groups, Genetic Variation, *Genetics, Population, Humans, Male, Mediterranean Region,

    Abstract: The Mediterranean region has been characterised by a number of pre-historical and historical demographic events whose legacy on the current genetic landscape is still a matter of debate. In order to investigate the degree of population structure across the Mediterranean, we have investigated Y chromosome variation in a large dataset of Mediterranean populations, 11 of which are first described here. Our analyses identify four main clusters in the Mediterranean that can be labelled as North Africa, Arab, Central-East and West Mediterranean. In particular, Near Eastern samples tend to separate according to the presence of Arab Y chromosome lineages, suggesting that the Arab expansion played a major role in shaping the current genetic structuring within the Fertile Crescent.

    Notes: Capelli, C, Redhead, N, Romano, V, Cali, F, Lefranc, G, Delague, V, Megarbane, A, Felice, A E, Pascali, V L, Neophytou, P I, Poulli, Z, Novelletto, A, Malaspina, P, Terrenato, L, Berebbi, A, Fellous, M, Thomas, M G, Goldstein, D B, Research Support, Non-U.S. Gov't, England, Annals of human genetics, Ann Hum Genet. 2006 Mar;70(Pt 2):207-25.,

    Author Address: Department of Biology, University College of London, London, UK. cristian.capelli@promega.com

    Language: eng