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    Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects

    Reference Type: Journal Article

    Record Number: 29

    Author: F. Di Giacomo, F. Luca, N. Anagnou, G. Ciavarella, R. M. Corbo, M. Cresta, F. Cucci, L. Di Stasi, V. Agostiano, M. Giparaki, A. Loutradis, C. Mammi, E. N. Michalodimitrakis, F. Papola, G. Pedicini, E. Plata, L. Terrenato, S. Tofanelli, P. Malaspina and A. Novelletto

    Year: 2003

    Title: Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects

    Journal: Mol Phylogenet Evol

    Volume: 28

    Issue: 3

    Pages: 387-95

    Epub Date: 2003/08/21

    Date: Sep

    Short Title: Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects

    ISSN: 1055-7903 (Print)

    DOI: S1055790303000162 [pii],

    Accession Number: 12927125

    Keywords: Analysis of Variance, Chromosomes, Human, Y/*genetics, DNA Primers, *Founder Effect, *Genetic Drift, *Genetic Variation, Geography, Greece, Haplotypes/genetics, Humans, Italy, Male, Microsatellite Repeats/genetics, Polymorphism, Single Nucleotide, Population Dynamics,

    Abstract: We explored the spatial distribution of human Y chromosomal diversity on a microgeographic scale, by typing 30 population samples from closely spaced locations in Italy and Greece for 9 haplogroups and their internal microsatellite variation. We confirm a significant difference in the composition of the Y chromosomal gene pools of the two countries. However, within each country, heterogeneity is not organized along the lines of clinal variation deduced from studies on larger spatial scales. Microsatellite data indicate that local increases of haplogroup frequencies can be often explained by a limited number of founders. We conclude that local founder or drift effects are the main determinants in shaping the microgeographic Y chromosomal diversity.

    Notes: Di Giacomo, F, Luca, F, Anagnou, N, Ciavarella, G, Corbo, R M, Cresta, M, Cucci, F, Di Stasi, L, Agostiano, V, Giparaki, M, Loutradis, A, Mammi', C, Michalodimitrakis, E N, Papola, F, Pedicini, G, Plata, E, Terrenato, L, Tofanelli, S, Malaspina, P, Novelletto, A, Comparative Study, Research Support, Non-U.S. Gov't, United States, Molecular phylogenetics and evolution, Mol Phylogenet Evol. 2003 Sep;28(3):387-95.,

    Author Address: Tor Vergata University, Rome, Italy.

    Language: eng