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    Population genetic study in two Transylvanian populations using forensically informative autosomal and Y-chromosomal STR markers


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    Reference Type: Journal Article

    Record Number: 31

    Author: B. Egyed, S. Furedi and Z. Padar

    Year: 2006

    Title: Population genetic study in two Transylvanian populations using forensically informative autosomal and Y-chromosomal STR markers

    Journal: Forensic Sci Int

    Volume: 164

    Issue: 2-3

    Pages: 257-65

    Epub Date: 2005/11/30

    Date: Dec 20

    Short Title: Population genetic study in two Transylvanian populations using forensically informative autosomal and Y-chromosomal STR markers

    ISSN: 0379-0738 (Print)

    DOI: S0379-0738(05)00593-1 [pii], 10.1016/j.forsciint.2005.10.020,

    Accession Number: 16314060

    Keywords: *Chromosomes, Human, Y, DNA Fingerprinting, Female, *Gene Frequency, *Genetics, Population, Humans, Male, Polymerase Chain Reaction, Romania, *Tandem Repeat Sequences,

    Abstract: Our study provides population genetic data on two population samples collected in a Hungarian speaking region of Transylvania, Romania. Allele frequency and profile databases were generated on 17 autosomal STR loci (D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, VWA, FGA, TH01, TPOX, CSF1PO, Penta E and Penta D) as well as at the 12 European Y-STR extended haplotype loci (DYS19, DYS389-I/II, DYS390, DYS391, DYS392, DYS393, DYS385 loci, DYS437, DYS438 and DYS439). Data were compared to a Central Hungarian (Budapest region) population sample [B. Egyed, S. Furedi, M. Angyal, L. Boutrand, A. Vandenberghe, J. Woller, Z. Padar, Analysis of eight STR loci in two Hungarian populations, Forensic Sci. Int. 113 (2000) 25-27] that was used as a reference group of the Hungarian population. Calculating the F(ST) indices and with the pairwise comparisons of interpopulation molecular variance (AMOVA) the two populations from Transylvania could be fit into the Hungarian population data showing less substructuring effects as compared to the previous findings in Hungary [B. Egyed, S. Furedi, M. Angyal, L. Boutrand, A. Vandenberghe, J. Woller, Z. Padar, Analysis of eight STR loci in two Hungarian populations, Forensic Sci. Int. 113 (2000) 25-27; B. Egyed, S. Furedi, M. Angyal, I. Balogh, L. Kalmar, Z. Padar, Analysis of the population heterogeneity in Hungary using fifteen forensically informative STR markers, Forensic Sci. Int. 158 (2005) 244-249].

    Notes: Egyed, Balazs, Furedi, Sandor, Padar, Zsolt, Ireland, Forensic science international, Forensic Sci Int. 2006 Dec 20;164(2-3):257-65. Epub 2005 Nov 28.,

    Author Address: Department of Haemogenetics, Institute for Forensic Sciences, H-1903 Budapest, Hungary. balazs.egyed@mail.orfk.b-m.hu

    Language: eng