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    Slow and fast evolving markers typing in Modena males (North Italy)


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    Reference Type: Journal Article

    Record Number: 34

    Author: G. Ferri, M. Alu, B. Corradini, E. Radheshi and G. Beduschi

    Year: 2009

    Title: Slow and fast evolving markers typing in Modena males (North Italy)

    Journal: Forensic Sci Int Genet

    Volume: 3

    Issue: 2

    Pages: e31-3

    Epub Date: 2009/02/14

    Date: Mar

    Short Title: Slow and fast evolving markers typing in Modena males (North Italy)

    ISSN: 1878-0326 (Electronic)

    DOI: S1872-4973(08)00082-3 [pii], 10.1016/j.fsigen.2008.05.004,

    Accession Number: 19215863

    Keywords: *Chromosomes, Human, Y, *DNA Fingerprinting, Evolution, Molecular, Gene Frequency, *Genetic Markers, Genetic Variation, *Genetics, Population, Geography, Haplotypes, Humans, Italy, Male, *Microsatellite Repeats, *Polymorphism, Single Nucleotide, Quality Control,

    Abstract: One hundred thirty male individuals, strictly selected for their geographical origin and for typical regional surnames were submitted to the analysis. 17 STRs (short tandem repeats) loci and 19 SNPs binary markers (single nucleotide polymorphisms) of male-specific region of the Y chromosome (MSY) were typed to well characterize the selected population of Modena province. The availability of joint distribution of MSY haplotypes and haplogroup frequencies is becoming an important tool for both human evolutionary studies and forensic investigation, but large databases of complete Y-lineages are needed for a better understanding of the power of the combined use of Y-specific polymorphisms. A total of 129 haplotypes and 9 haplogroups were found and R1b haplogroup with a frequency of 67.7% was the most frequent, as expected because of the geographical location of the sample (Northwestern Italy). The Modena Y-lineages (STRs and SNPs independently) were also compared with published data of other neighbouring populations' samples.

    Notes: Ferri, Gianmarco, Alu, Milena, Corradini, Beatrice, Radheshi, Erjon, Beduschi, Giovanni, Netherlands, Forensic science international. Genetics, Forensic Sci Int Genet. 2009 Mar;3(2):e31-3. Epub 2008 Jun 20.,

    Author Address: Department of Diagnostic and Laboratory Service and Legal Medicine, Section of Legal Medicine, University of Modena and Reggio Emilia, Italy. gianmarco.ferri@unimore.it

    Language: eng