Работает база данных...



    • Main Page
    • SOURCES: Papers on Y сhromosomal variation

    Reduced Y-chromosome, but not mitochondrial DNA, diversity in human populations from West New Guinea


    У вас нет прав на скачивание файла
    Login:
    Password:
    Register
    Forgot your password?

    Reference Type: Journal Article

    Record Number: 54

    Author: M. Kayser, S. Brauer, G. Weiss, W. Schiefenhovel, P. Underhill, P. Shen, P. Oefner, M. Tommaseo-Ponzetta and M. Stoneking

    Year: 2003

    Title: Reduced Y-chromosome, but not mitochondrial DNA, diversity in human populations from West New Guinea

    Journal: Am J Hum Genet

    Volume: 72

    Issue: 2

    Pages: 281-302

    Epub Date: 2003/01/18

    Date: Feb

    Short Title: Reduced Y-chromosome, but not mitochondrial DNA, diversity in human populations from West New Guinea

    ISSN: 0002-9297 (Print)

    DOI: S0002-9297(07)60539-4 [pii], 10.1086/346065,

    Accession Number: 12532283

    Keywords: Chromosomes, Human, Y/*genetics, *DNA, Mitochondrial/analysis, Gene Frequency, Genetic Markers, *Genetic Variation, Haplotypes, Humans, Indonesia, Male, Pacific Islands, Papua New Guinea, Tandem Repeat Sequences,

    Abstract: To investigate the paternal population history of New Guinea, 183 individuals from 11 regional populations of West New Guinea (WNG) and 131 individuals from Papua New Guinea (PNG) were analyzed at 26 binary markers and seven short-tandem-repeat loci from the nonrecombining part of the human Y chromosome and were compared with 14 populations of eastern and southeastern Asia, Polynesia, and Australia. Y-chromosomal diversity was low in WNG compared with PNG and with most other populations from Asia/Oceania; a single haplogroup (M-M4) accounts for 75% of WNG Y chromosomes, and many WNG populations have just one Y haplogroup. Four Y-chromosomal lineages (haplogroups M-M4, C-M208, C-M38, and K-M230) account for 94% of WNG Y chromosomes and 78% of all Melanesian Y chromosomes and were identified to have most likely arisen in Melanesia. Haplogroup C-M208, which in WNG is restricted to the Dani and Lani, two linguistically closely related populations from the central and western highlands of WNG, was identified as the major Polynesian Y-chromosome lineage. A network analysis of associated Y-chromosomal short-tandem-repeat haplotypes suggests two distinct population expansions involving C-M208--one in New Guinea and one in Polynesia. The observed low levels of Y-chromosome diversity in WNG contrast with high levels of mtDNA diversity reported for the same populations. This most likely reflects extreme patrilocality and/or biased male reproductive success (polygyny). Our data further provide evidence for primarily female-mediated gene flow within the highlands of New Guinea but primarily male-mediated gene flow between highland and lowland/coastal regions.

    Notes: Kayser, Manfred, Brauer, Silke, Weiss, Gunter, Schiefenhovel, Wulf, Underhill, Peter, Shen, Peidong, Oefner, Peter, Tommaseo-Ponzetta, Mila, Stoneking, Mark, Comparative Study, Research Support, Non-U.S. Gov't, United States, American journal of human genetics, Am J Hum Genet. 2003 Feb;72(2):281-302. Epub 2002 Jan 16.,

    Author Address: Department for Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. kayser@eva.mpg.de

    Language: eng