У вас нет прав на скачивание файла
Reference Type: Journal Article
Record Number: 61
Author: V. N. Khar'kov, V. A. Stepanov, S. A. Borinskaia, M. Kozhekbaeva Zh, V. A. Gusar, E. Grechanina, V. P. Puzyrev, E. K. Khusnutdinova and N. K. Iankovskii
Title: [Structure of the gene pool of eastern Ukrainians from Y-chromosome haplogroups]
Epub Date: 2004/05/06
Short Title: [Structure of the gene pool of eastern Ukrainians from Y-chromosome haplogroups]
ISSN: 0016-6758 (Print)
Accession Number: 15125258
Keywords: Base Sequence, *Chromosomes, Human, Y, DNA Primers, *Gene Pool, *Haplotypes, Humans, Ukraine,
Abstract: Y chromosomes from representative sample of Eastern Ukrainians (94 individuals) were analyzed for composition and frequencies of haplogroups, defined by 11 biallelic loci located in non-recombining part of the chromosome (SRY1532, YAP, 92R7, DYF155S2, 12f2, Tat, M9, M17, M25, M89, and M56). In the Ukrainian gene, pool six haplogroups were revealed: E, F (including G and I), J, N3, P, and R1a1. These haplogroups were earlier detected in a study of Y-chromosome diversity on the territory of Europe as a whole. The major haplogroup in the Ukrainian gene pool, haplogroup R1a1 (earlier designated HG3), accounted for about 44% of all Y chromosomes in the sample examined. This haplogroup is thought to mark the migration patterns of the early Indo-Europeans and is associated with the distribution of the Kurgan archaeological culture. The second major haplogroup is haplogroup F (21.3%), which is a combination of the lineages differing by the time of appearance. Haplogroup P found with the frequency of 9.6%, represents the genetic contribution of the population originating from the ancient autochthonous population of Europe. Haplogroups J and E (11.7 and 4.2%, respectively) mark the migration patterns of the Middle-Eastern agriculturists during the Neolithic. The presence of the N3 lineage (9.6%) is likely explained by a contribution of the assimilated Finno-Ugric tribes. The data on the composition and frequencies of Y-chromosome haplogroups in the sample studied substantially supplement the existing picture of the male lineage distribution in the Eastern Slav population.
Notes: Khar'kov, V N, Stepanov, V A, Borinskaia, S A, Kozhekbaeva, Zh M, Gusar, V A, Grechanina, E Ia, Puzyrev, V P, Khusnutdinova, E K, Iankovskii, N K, English Abstract, Russia, Genetika, Genetika. 2004 Mar;40(3):415-21.,
Author Address: Institute of Medical Genetics, Tomsk Research Center, Russian Academy of Medical Sciences, Tomsk, 634050 Russia.