Работает база данных...



    • Main Page
    • SOURCES: Papers on Y сhromosomal variation

    Y-chromosomal binary haplogroups in the Japanese population and their relationship to 16 Y-STR polymorphisms


    У вас нет прав на скачивание файла
    Login:
    Password:
    Register
    Forgot your password?

    Reference Type: Journal Article

    Record Number: 107

    Author: I. Nonaka, K. Minaguchi and N. Takezaki

    Year: 2007

    Title: Y-chromosomal binary haplogroups in the Japanese population and their relationship to 16 Y-STR polymorphisms

    Journal: Ann Hum Genet

    Volume: 71

    Issue: Pt 4

    Pages: 480-95

    Epub Date: 2007/02/06

    Date: Jul

    Short Title: Y-chromosomal binary haplogroups in the Japanese population and their relationship to 16 Y-STR polymorphisms

    ISSN: 0003-4800 (Print)

    DOI: AHG343 [pii], 10.1111/j.1469-1809.2006.00343.x,

    Accession Number: 17274803

    Keywords: Asian Continental Ancestry Group/*genetics, Chromosomes, Human, Y/*genetics, *Genetics, Population, *Haplotypes, Humans, Microsatellite Repeats, Polymorphism, Genetic, Tandem Repeat Sequences/*genetics,

    Abstract: We investigated Y chromosomal binary and STR polymorphisms in 263 unrelated male individuals from the Japanese population and further examined the relationships between the two separate types of data. Using 47 biallelic markers we distinguished 20 haplogroups, four of which (D2b1/-022457, O3/-002611*, O3/-LINE1 del, and O3/-021354*) were newly defined in this study. Most haplogroups in the Japanese population are found in one of the three major clades, C, D, or O. Among these, two major lineages, D2b and O2b, account for 66% of Japanese Y chromosomes. Haplotype diversity of binary markers was calculated at 86.3%. The addition of 16 Y-STR markers increased the number of haplotypes to 225, yielding a haplotype diversity of 99.40%. A comparison of binary haplogroups and Y-STR type revealed a close association between certain binary haplogroups and Y-STR allelic or conformational differences, such as those at the DXYS156Y, DYS390m, DYS392, DYS437, DYS438 and DYS388 loci. Based on our data on the relationships between binary and STR polymorphisms, we estimated the binary haplogroups of individuals from STR haplotypes and frequencies of binary haplogroups in other Japanese, Korean and Taiwanese Han populations. The present data will enable researchers to connect data from binary haplogrouping in anthropological studies and Y-STR typing in forensic studies in East Asian populations, especially those in and around Japan.

    Notes: Nonaka, I, Minaguchi, K, Takezaki, N, Research Support, Non-U.S. Gov't, England, Annals of human genetics, Ann Hum Genet. 2007 Jul;71(Pt 4):480-95. Epub 2007 Feb 2.,

    Author Address: Department of Forensic Odontology, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba City, 261-0011, Japan.

    Language: eng