Работает база данных...



    • Main Page
    • SOURCES: Papers on Y сhromosomal variation

    A counter-clockwise northern route of the Y-chromosome haplogroup N from Southeast Asia towards Europe


    У вас нет прав на скачивание файла
    Login:
    Password:
    Register
    Forgot your password?

    Reference Type: Journal Article

    Record Number: 131

    Author: S. Rootsi, L. A. Zhivotovsky, M. Baldovic, M. Kayser, I. A. Kutuev, R. Khusainova, M. A. Bermisheva, M. Gubina, S. A. Fedorova, A. M. Ilumae, E. K. Khusnutdinova, M. I. Voevoda, L. P. Osipova, M. Stoneking, A. A. Lin, V. Ferak, J. Parik, T. Kivisild, P. A. Underhill and R. Villems

    Year: 2007

    Title: A counter-clockwise northern route of the Y-chromosome haplogroup N from Southeast Asia towards Europe

    Journal: Eur J Hum Genet

    Volume: 15

    Issue: 2

    Pages: 204-11

    Epub Date: 2006/12/07

    Date: Feb

    Short Title: A counter-clockwise northern route of the Y-chromosome haplogroup N from Southeast Asia towards Europe

    ISSN: 1018-4813 (Print)

    DOI: 5201748 [pii], 10.1038/sj.ejhg.5201748,

    Accession Number: 17149388

    Keywords: Asia, Southeastern, Chromosomes, Human, Y/*classification/*genetics, Europe, Eastern, *Genetics, Population, *Haplotypes, Humans, Male, Phylogeny, Sequence Analysis, DNA,

    Abstract: A large part of Y chromosome lineages in East European and East Asian human populations belong to haplogroup (hg) NO, which is composed of two sister clades N-M231 and O-M175. The O-clade is relatively old (around 30 thousand years (ky)) and encompasses the vast majority of east and Southeast Asian male lineages, as well as significant proportion of those in Oceanian males. On the other hand, our detailed analysis of hg N suggests that its high frequency in east Europe is due to its more recent expansion westward on a counter-clock northern route from inner Asia/southern Siberia, approximately 12-14 ky ago. The widespread presence of hg N in Siberia, together with its absence in Native Americans, implies its spread happened after the founder event for the Americas. The most frequent subclade N3, arose probably in the region of present day China, and subsequently experienced serial bottlenecks in Siberia and secondary expansions in eastern Europe. Another branch, N2, forms two distinctive subclusters of STR haplotypes, Asian (N2-A) and European (N2-E), the latter now mostly distributed in Finno-Ugric and related populations. These phylogeographic patterns provide evidence consistent with male-mediated counter-clockwise late Pleistocene-Holocene migratory trajectories toward Northwestern Europe from an ancestral East Asian source of Paleolithic heritage.

    Notes: Rootsi, Siiri, Zhivotovsky, Lev A, Baldovic, Marian, Kayser, Manfred, Kutuev, Ildus A, Khusainova, Rita, Bermisheva, Marina A, Gubina, Marina, Fedorova, Sardana A, Ilumae, Anne-Mai, Khusnutdinova, Elza K, Voevoda, Mikhail I, Osipova, Ludmila P, Stoneking, Mark, Lin, Alice A, Ferak, Vladimir, Parik, Juri, Kivisild, Toomas, Underhill, Peter A, Villems, Richard, Research Support, Non-U.S. Gov't, England, European journal of human genetics : EJHG, Eur J Hum Genet. 2007 Feb;15(2):204-11. Epub 2006 Dec 6.,

    Author Address: Department of Evolutionary Biology, University of Tartu and Estonian Biocentre, Tartu, Estonia. sroots@ebc.ee

    Language: eng