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    Haplotype diversity of 22 Y-chromosomal STRs in a southeast China population sample (Chaoshan area)


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    Reference Type: Journal Article

    Record Number: 142

    Author: M. Shi, R. Bai, X. Yu, J. Lv and B. Hu

    Year: 2009

    Title: Haplotype diversity of 22 Y-chromosomal STRs in a southeast China population sample (Chaoshan area)

    Journal: Forensic Sci Int Genet

    Volume: 3

    Issue: 2

    Pages: e45-7

    Epub Date: 2009/02/14

    Date: Mar

    Short Title: Haplotype diversity of 22 Y-chromosomal STRs in a southeast China population sample (Chaoshan area)

    ISSN: 1878-0326 (Electronic)

    DOI: S1872-4973(08)00086-0 [pii], 10.1016/j.fsigen.2008.05.009,

    Accession Number: 19215866

    Keywords: Alleles, China, *Chromosomes, Human, Y, DNA Fingerprinting, Gene Frequency, Genetic Variation, *Genetics, Population, Geography, *Haplotypes, Humans, Male, *Microsatellite Repeats, Polymerase Chain Reaction,

    Abstract: In this study, 22 Y-specific STR loci (DYS19, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS461, DYS481, DYS504, DYS505, DYS508, DYS533, DYS576, DYS588, DYS607, DYS634, and DYS643) were analyzed in 216 unrelated male individuals from southeast China (Chaoshan area) by three multiplex PCR systems. The haplotype diversity using the classical set of Y-STRs (DYS19, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, and DYS385; PowerPlexY Systems) was 0.9908. For the same population sample, the haplotype diversity using the new sets of 11 novel Y-STRs (DYS461, DYS481, DYS504, DYS505, DYS508, DYS533, DYS576, DYS588, DYS607, DYS634, and DYS643; multiplex I and II) was 0.9917. By combining the allelic states of the 22 Y-STR loci we could construct highly informative haplotypes that allowed the discrimination of 99.1% (214 out of 216) of the samples tested and the overall haplotype diversity of 0.9999. These results, including the haplotype data at 22 Y-STR loci in the present study, provide useful information for forensic practice in the Chaoshan population in southeast China.

    Notes: Shi, Meisen, Bai, Rufeng, Yu, Xiaojun, Lv, Junyao, Hu, Bo, Research Support, Non-U.S. Gov't, Netherlands, Forensic science international. Genetics, Forensic Sci Int Genet. 2009 Mar;3(2):e45-7. Epub 2008 Jul 7.,

    Author Address: Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Eduction 25 Xitucheng Road, Haidian District, Beijing 100088, PR China. shimeisen2000@yahoo.com.cn

    Language: eng